##article.abstract##
Gastrointestinal nematodes are the most common parasites found in ruminants in the world. These parasites cause parasitic gastroenteritis and have a negative effect on productivity. Nematode control has been based on the use of anthelmintic chemicals—against which nematodes have developed a certain degree of resistance—which have been rated as residual substances in goat products that may cause adverse effects on the final consumer. As a result, the study of plant components has been proposed as a sustainable alternative to control nematodosis in goats. The anthelmintic potential of aqueous extracts of <em>Nicotiana tabacum </em>and oily extracts of <em>Azadirachta indica </em>on gastrointestinal nematodes affecting the goat chain was evaluated <em>in vitro </em>in this study. Nematicidal activity tests were performed on stool samples from goats with a high parasite load (trichostrongyles), by performing dose/ response curves. Percent inhibition in egg hatch for the aqueous extract of <em>N. tabacum </em>and the oily extract of <em>A. indica </em>was 99% and 80%, respectively. Extracts showed an effect on larva 3 (infective stage), with a mean lethal time of 8 ± 1 minutes for extracts of N. <em>Tabacum, </em>and of 8 ± 1 minutes for extract of <em>A. indica. </em>The <em>in vitro </em>results of the nematicidal activity show that <em>N. tabacum </em>and <em>A. indica </em>extracts can be a promising alternative for controlling nematodes in ruminants.
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