Prevalence and risk factors of equine gastric ulcer syndrome at a single sport horse facility
Revista de Medicina Veterinaria

Abstract

Equine gastric ulcer syndrome (EGUS) is a common disease that impacts horse welfare. The objective of this study was to estimate the prevalence of gastric ulcers of the squamous and glandular portions, and simultaneous presentation and to determine their risk factors in sport horses at an equestrian complex in Colombia. These 50 horses showed that 23 (46%) had gastric ulcer (GU) in any of the stomach portions, 15 (30%) had Equine Squamous Gastric Disease (ESGD), 17 (34%) had Equine Gastric Glandular Disease (EGGD) and 9 (18%) presented ESGD and EGGD. In the affected horses, 26.09% presented ESGD, 34.78% EGGD and 39.13% ESGD and EGGD simultaneously. A significant association was found between GU in any portion with: breed (OR = 2.36, CI = 1.116-3.262), colic event during last year (OR = 2.516, CI = 1.63-10.042), previous diagnosis of GU (OR = 2.476, CI = 1.21-29.227) and with not being stabled (OR = 5.479 CI = 2.566-52.969). The study also showed an association between EGGD with concentrate consumption at < 2 kg/meal (OR = 2.095, CI = 1.599-7.333), having < 2 hours of grazing daily (OR = 4.636, CI = 1.684-31.435) and not being stabled (OR = 5.032, CI = 1.004-21.405). There was also a significant association between GU in both portions and previous diagnosis of GU (OR = 2.438, CI = 2.196-30.337). The presentation of the disease between the different stomach portions was significantly associated (p < 0.05). The results showed a significant prevalence of EGUS (46%) in the horses at the equestrian complex and it helped determine several associated risk factors.

PDF

References

Andrews F, Buchanan B, Elliot S, Clariday N, Edwards L. Gastric ulcers in horses 1. J. Anim Sci. 2005;83 (Suppl.):E18–E2. https://doi.org/10.2527/2005.8313_supplE18x

Van den Boom R. Equine gastric ulcer syndrome in adult horses. Vet J. 2022;(283–284);105830. https://doi.org/10.1016/j.tvjl.2022.105830

Begg LM, O’Sullivan CB. The prevalence and distribution of gastric ulceration in 345 racehorses. Aust Vet J. 2003;81(4):199–201. https://doi.org/10.1111/j.1751-0813.2003.tb11469.x

Luthersson N, Nielsen K, Harris P, Parkin T. The prevalence and anatomical distribution of equine gastric ulceration syndrome (egus) in 201 horses in Denmark. Equine Vet J. 2009;41(7):619–24. https://doi.org/10.2746/042516409X441910

Sykes BW, Hewetson M, Hepburn RJ, Luthersson N, Tamzali Y. European College of Equine Internal Medicine Consensus Statement-Equine Gastric Ulcer Syndrome in Adult Horses. J Vet Intern Med. 2015;29(5):1288–99. https://doi.org/10.1111/jvim.13578

Sykes BW, Jokisalo JM. Rethinking equine gastric ulcer syndrome. Part 2 – Equine squamous gastric ulcer syndrome (esgus). Equine Vet Educ. 2015;27(5):264–8. https://doi.org/10.1111/eve.12277

Sandin A, Skidell J, Haggstrom J, Nilson G. Postmortem findings of gastric ulcers in Swedish horses older than age one year: a retrospective study of 3715 horses (1924-1996). Equine Vet J. 2000;32(1):36–42. https://doi.org/10.2746/042516400777612044

Chameroy KA, Nadeau JA, Bushmish SL, Dinger JE, Hoagland TH, Saxton AM. Prevalence of non-glandular gastric ulcers in horses involved in a university riding program. J Equine Vet Sci. 2006;26(5):207–11. https://doi.org/10.1016/j.jevs.2006.03.001

Vatistas NJ, Sifferman RL, Holste J, Cox JL, Pinalto G, Schultz KT. Induction and maintenance of gastric ulceration in horses in simulated race training. Equine Vet J. 1999;(29):40–4. https://doi.org/10.1111/j.2042-3306.1999.tb05167.x

Lorenzo-Figueras M, Merrit AM. Effects of exercise on gastric volume and pH in the proximal portion of the stomach of horses. AJVR. 2002;63(11):1481–7. https://doi.org/10.2460/ajvr.2002.63.1481

Tamzali Y, Marguet C, Priymenko N, Lyazrhi F. Prevalence of gastric ulcer syndrome in high level endurance horses. Equine Vet J. 2011;43(2):141–4. https://doi.org/10.1111/j.2042-3306.2010.00129.x

Jhonsson H, Egenvall A. Prevalence of gastric ulceration in Swedish Standardbreds in race training. Equine Vet J. 2006;38(3):209–13. https://doi.org/10.2746/042516406776866390

McClure SR, Glickman LT, Glickman NW. Prevalence of gastric ulcers in show horses. JAVMA. 1999;215(8):1130–3. https://doi.org/10.2460/javma.1999.215.08.1130

Paladino B, Raidal SL, Hall E, Knight P, Celi P, Jeffcott L, et al. Risk factors in equine transport-related health problems: A survey of the Australian Equine Industry. Equine Vet J. 2017;49(4):507–11. https://doi.org/10.1111/evj.12631

Murray MJ, Eichorn ES. Effects of intermittent feed deprivation, intermittent feed deprivation with ranitidine administration, and stall confinement with ad libitum access to hay on gastric ulcerations in horses. Am J Vet. 1996;57(11):1599–1603. https://doi.org/10.2460/ajvr.1996.57.11.1599

Luthersson N, Nielsen K, Harris P, Parkin T. Risk factor associated with equine gastric ulceration syndrome (egus) in 201 horses in Denmark. Equine Vet J. 2009;41(7):625–30. https://doi.org/10.2746/042516409X441929

Sykes BW, Underwood C, Mills PC. The effects of dose and diet on the pharmacodynamics of esomeprazole in the horse. Equine Vet J. 2017;49:637–42. https://doi.org/10.1111/evj.12670

Lester GD, Robinson I, Secombe C. Risk factors for gastric ulceration in Thoroughbred racehorses. Murdoch (AU): Australian Government: Rural Industries Research and Development Corporation; 2008.

Orsini JA, Hackett ES, Grenager N. The effect of exercise on Equine Gastric Ulcer Syndrome in the Thoroughbred and Standardbred athlete. J Equine Vet Sci. 2009;29(3):167–71. https://doi.org/10.1016/j.jevs.2009.01.006

Monki J, Hewetson M, Virtala A. Risk factors for equine gastric glandular disease: A case-control study in a Finnish referral hospital population. J Vet Intern Med. 2016;30(4):1270–5. https://doi.org/10.1111/jvim.14370

Habershon-Butcher J, Hallowed G, Bowen I, Sykes B. Prevalence and risk factors for ulceration of the gastric glandular mucosa in Thoroughbred racehorses in training in the UK and Australia. J Vet Intern Med. 2012;26:731.

Malmkvist J, Moller J, Luthersson N, Palme P, Winter J, Sondergaard E. Behaviour and stress responses in horses with gastric ulceration. Appl Anim Behav Sci. 2012;142(3-4):160–7. https://doi.org/10.1016/j.applanim.2012.10.002

McClure SR, Carithers DS, Gross SJ, Murray MJ. Gastric ulcer development in horses in a simulated show or training environment. JAVMA. 2005;227(5):775–7. https://doi.org/10.2460/javma.2005.227.775

Withfield C, Richardson L, Chamoun A, Cohen ND. Differential effects of selective and nonselective cyclooxygenase inhibitors on gastric ulceration scores, intestinal inflammation, fecal microbiota, and composition and diversity in adult horses. Equine Vet Educ. 2017; 29(58):9. https://doi.org/10.1111/eve.11_12792

Sykes BW, Bowen M, Habershon-Butcher JL, Green M, Hallowell GD. Management factors and clinical implications of glandular and squamous gastric disease in horses. J Vet Int Med. 2019;33:233–40. https://doi.org/10.1111/jvim.15350

Sykes BW, Jokisalo JM. Rethinking equine gastric ulcer syndrome. Part 1 - Terminology, clinical signs and diagnosis. Equine Vet Educ. 2014;26(10):543–7. https://doi.org/10.1111/eve.12236

Andrews F, Bernard WV, Byars D. Recommendations for the diagnosis and treatment of equine gastric ulcer syndrome (egus): The Equine Gastric Ulcer Council. Equine Vet Educ. 1999;11(5):262–72. https://doi.org/10.1111/j.2042-3292.1999.tb00961.x

Murray MJ, Nout YS, Ward DL. Endoscopic findings of the gastric antrum and pylorus in horses: 162 cases (1996-2000). J Vet Intern. 2001;15(4):401–6. https://doi.org/10.1111/j.1939-1676.2001.tb02336.x

Gordis L. The occurrence of disease: I. Disease Surveillance and Measures of Morbidity. In: Epidemiology. 5th ed. Philadelphia (US):Elsevier Saunders; 2014. p. 38–60.

Hosmer D. Lemeshow S. Applied Logistic Regression (Wiley series in probability and statistics). Toronto (CA): John Wiley and Sons, Inc.; 2000. https://doi.org/10.1002/0471722146

Henneke D, Potter G, Krider J, Yeates B. Relationship between condition score, physical measurements and body fat percentage in mares. Equine Vet J. 1983;15(4):371–2. https://doi.org/10.1111/j.2042-3306.1983.tb01826.x

Niedzwiedz A, Kubiak K, Nicpon J. Endoscopic findings of the stomach in pleasure horses in Poland. Acta Vet Scand. 2013;55:45. https://doi.org/10.1186/1751-0147-55-45

Bell RJW, Kingston JK, Mogg TD, Perkins NR. A comparison of two scoring systems for endoscopic grading of gastric ulceration in horses. N Z Vet J. 2007;55(1):19–22. https://doi.org/10.1080/00480169.2007.36730

Murray M. Gastric ulcerations in horses: 91 cases (1987-1990). JAVMA. 1992;201(1):117–120. https://doi.org/10.2460/javma.1992.201.01.117

Dione RM, Vrins A, Doucet MY, Paré J. Gastric ulcers in Standardbred racehorses: prevalence, lesion description, and risk factors. J Vet Inter Med. 2003;17(2):218–22. https://doi.org/10.1111/j.1939-1676.2003.tb02437.x

Hewetson M, Sykes B, Hallowell G, Tulamo R. Diagnostic accuracy of blood sucrose as a screening test for equine gastric ulcer syndrome (egus) in adult horses. Acta Vet Scand. 2017;59(1):15. https://doi.org/10.1186/s13028-017-0284-1

Nieto JE, Snyder JR, Beldomenico P, Aleman M, Kerr JW, Spier SJ. Prevalence of gastric ulcers in endurance horses – A preliminary report. Vet J. 2004;167(1):33–7. https://doi.org/10.1016/j.tvjl.2003.09.005

MacAllister CG, Andrews FM, Deegans E, Rouff W, Olovsonfl SG. A scoring system for gastric ulcers in the horse. Equine Vet J. 1997;29(6):430–3. https://doi.org/10.1111/j.2042-3306.1997.tb03154.x

Videla R, Andrews FM. New perspectives in Equine Gastric Ulcer Syndrome. Vet Clin of North Am. Equine Pract. 2009;25(2):283–301. https://doi.org/10.1016/j.cveq.2009.04.013

Hepburn RJ. Endoscopic examinations of the squamous and glandular gastric mucosa in sport and leisure horses: 684 horses (2005-2011). BMC Vet. 2014;10:1–11.

MacLeod H, Windeyer C, Crosby C, Banse H. Prevalence and risk factors for gastric ulceration in polo horses. J Vet Intern Med. 2015;29:1239–40.

Ward S, Sykes BW, Brown H, Bishop A, Penaluna LA. A comparison of the prevalence of gastric ulceration in feral and domesticated horses in the UK. Equine Vet Educ. 2015;27(12):655–7. https://doi.org/10.1111/eve.12491

Ḉentikaya MA, Demirutku A, Kaya M. Gastroscopic evaluation of gastric ulcer syndrome in sport horses with poor performance. Turk J Vet Anim Sci. 2013:37(5):541–5. https://doi.org/10.3906/vet-1209-38

Husted L, Sánchez LC, Olsen SN, Baptiste KE, Merrit AM. Effect of paddock vs. housing on 24 hour gastric pH within the proximal and ventral equine stomach. Equine Vet J. 2008;40(4):337–41 https://doi.org/10.2746/042516408X284673

Buchanan B, Andrews F. Treatment and prevention of equine gastric ulcer syndrome. Vet Clin North Am Equine Pract. 2003;19(3):575–97. https://doi.org/10.1016/j.cveq.2003.08.012

Andrews FM, Larson C, Harris P. Nutritional management of gastric ulceration. Equine Vet Educ. 2017;29(1):45–55. https://doi.org/10.1111/eve.12495

Woodward MC, Huff NK, Garza F, Keowen ML, Kearney MT, Andrews FM. Effect of pectin, lecithin and antiacid feed supplements (Egusin®) on gastric ulcer scores, gastric fluid pH and blood gas values in horses. BMC Vet. 2014;10:S4. https://doi.org/10.1186/1746-6148-10-S1-S4

Sandin A, Girma K, Sjoholm B, Lindholm A, Nilsson G. Effects of differently composed feeds and physical stress on plasma gastrin concentration in horses. Acta Vet Scand. 1998;39(2):265–72. https://doi.org/10.1186/BF03547798

Morales A. A Retrospective Study of Mortality Causes in Arabian Horses. Rev Med Vet. 2020;(41):23–31. https://doi.org/10.19052/mv.vol1.iss41.3

Morales A, Méndez A. Histopathological Detection of Helicobacter like Organism in Gastric Mucosa of Spanish Horses. Intern J Appl Res Vet Med. 2013;11(3):174–9.

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Metrics

Metrics Loading ...

Downloads

Download data is not yet available.
Créditos: Laura María Acosta Cañas

Keywords

EGUS
equine
gastric
gastroscopy
ulcer

How to Cite

Triana Ospina, J. A., & Oliver Espinosa, O. J. (2025). Prevalence and risk factors of equine gastric ulcer syndrome at a single sport horse facility. Revista De Medicina Veterinaria, 50, e5397. https://doi.org/10.19052/mv.vol1.iss50.5397