Hematological Reference Intervals Milk-Fed Calves During the First Four Weeks upon Arrival to the Farm
Revista de Medicina Veterinaria

Resumen

El objetivo de esta investigación fue establecer los intervalos de referencia hematológicos de los terneros alimentados con lactorreemplazador durante las primeras cuatro semanas de llegada al sistema de producción. Se utilizaron 80 neonatos Holstein lecheros (de 2 a 7 días de edad). Todos los terneros fueron alimentados con sustituto de leche propicia para este sistema de producción, dos veces al día. Las muestras de sangre para establecer los intervalos de referencia hematológicos en estos terneros se tomaron 24 horas después del arribo, a los 7 días, 14 días, 21 días y 28 días (5 muestras en 4 semanas). Se realizó un hemograma completo y medición de proteínas séricas totales, además, los terneros se pesaron a las 24 h y al día 28 después de su llegada. Se obtuvieron parámetros expresados en rangos mínimos y máximos de WBC 3.5 a 53.6 cellx109/L; neutrófilos segmentados 46,6 – 0,43 cellx109/L, linfocitos 13,4 – 1,1 cellx109/L; monocitos 2,7 – 0,2 cellx109/L; eosinófilos 0 - 0,8 célulasx109/L; basófilos 0 - 0.5 cellx109/L, RBC 5.2 a 12.1 cellx1012/L; HGB 61 a 153 g/L; HTC 0,18 a 0,45 L/L, MCV 24 a 47 fL, MCH 8 a 15 pg; y MCHC 298 a 354 g/L. Para estos 5 tiempos de muestreo, la proteína sérica total fue x̅ 5.11 g/100 mL, 4.76 g/100 mL, 4.63 g/100 mL, 4.65 g/100 mL y 5.14 g/100 mL. Se registró un aumento de peso x̅ 51,82 kg (mínimo 31.8 y máximo 72.6 kg). Dada la inexistencia de parámetros sanguíneos de referencia en este tipo de terneros, este estudio proporciona las bases para sustentar parámetros de referencia iniciales durante las primeras 4 semanas de llegada a los sistemas de producción (animales entre 30 y 37 días de edad).

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Referencias

De Vries A, Overton M, Fetrow J, Leslie K, Eicker S, Rogers

G. Exploring the Impact of Sexed Semen on the Structure of the Dairy Industry. J Dairy Sci. 2008;91(2):847-856. https://doi.org/10.3168/jds.2007-0536

Winder CB, Kelton DF, Duffield TF. Mortality risk fac- tors for calves entering a multi-location white veal farm in Ontario, Canada. J Dairy Sci. 2016;99(12):10174- 10181. https://doi.org/10.3168/jds.2016-11345

Statistics Canada. Table 32-10-0130-01. Number of cattle, by class and farm type (x1000). 2023. https://doi. org/10.25318/3210013001-eng

Pardon BB, Catry R, Boone H, Theys K, De Bleecker J, Dewulf P. Characteristics and challenges of the modern Belgian veal. Vlaams Diergeneeskd. Tijdschr. 2014;83: 155-163. https://doi.org/10.21825/vdt.v83i4.16641

Sans P, De Fontguyon G. Veal calf industry econom- ics. Rev Med Vet-Toulouse. 2009;160(8–9):420-424. Available from: http://www.revmedvet.com/artdes-fr. php?id=1741

Gulliksen SM, Lie KI, Loken T, Osteras O. Calf mortal- ity in Norwegian dairy herds. J Dairy Sci. 2004;92(6): 2782-2795. https://doi.org/10.3168/jds.2008-1807

United States Department of Agriculture (USDA). Dairy 2007, heifer calf health and management practic- es on U.S. dairy operations. USDA – Animal and Plant Health Inspection Service – Veterinary Services, Cen- ter for Epidemiology and Animal Health, Fort Collins, CO. 2010. Available from: https://www.aphis.usda. gov/animal_health/nahms/dairy/downloads/dairy07/ Dairy07_ir_CalfHealth_1.pdf

Cho YI, Yoon KJ. An overview of calf diarrhea-Infec- tious etiology, diagnosis, and intervention. J Vet Sci. 2014;15(1):1-17. https://doi.org/10.4142/jvs.2014.15.1.1

Meganck V, Hoflack S, Piepers V, Opsomer G. Evalu- ation of a protocol to reduce the incidence of neonatal calf diarrhea on dairy herds. Prev Vet Med. 2015;118(1): 64-70.https://doi.org/10.1016/j.prevetmed.2014.11.007

Todd CG, Millman ST, McKnight DR, Duffield TF, Les- lie KE. Nonsteroidal anti-inflammatory drug therapy for neonatal calf diarrhea complex: Effects on calf per- formance. J Anim Sci. 2010;88(6):2019-2028. https:// doi.org/10.2527/jas.2009-2340

Schroeder ME, Bounpheng MA, Rodgers S, Baker RJ, Black W, Naikare H, et al. Development and per- formance evaluation of calf diarrhoea pathogen nucleic acid purification and detection workflow. J Vet Diagn Invest. 2012;24(5):945-953. https://doi. org/10.1177/1040638712456976

White BJ, Anderson DE, Renter DG, Larson RL, Mosier DA, Kelly LL, et al. Clinical, behavioral, and pulmonary changes in calves following inoculation with Mycoplas- ma bovis. Am J Vet Res. 2012;73(4):490-497. https:// doi.org/10.2460/ajvr.73.4.490

Weary DM, Huzzey JM, von Keyserlingk MAG. Board- invited review: Using behavior to predict and identify ill health in animals. J Anim Sci. 2009;87(2):770-777. https://doi.org/10.2527/jas.2008-1297

Pardon B, Hostens M, Duchateau L, Dewulf J, De Bleecker K, Deprez P. Impact of respiratory disease, diarrhea, otitis and arthritis on mortality and carcass traits in white veal calves. BMC Vet Res. 2013;9(1):79. https://doi.org/10.1186/1746-6148-9-79

de Graaf DC, Vanopdenbosch E, Ortega-Mora LM, Abbassi H, Peeters JE. A review of the importance of cryptosporidiosis in farm animals. Int J.Parasitol. 1999;29(8):1269-1287. https://doi.org/10.1016/S0020-

(99)00076-4

Lowe GL, Sutherland MA, Waas JR, Schaefer AL, Cox NR, Stewart M. Physiological and behavioral re- sponses as indicators for early disease detection in dairy calves. J Dairy Sci. 2019;102(6):5389-5402. https://doi. org/10.3168/jds.2018-15701

Kahn CM, Line S, Aiello SE. The Merck veterinary manual. 10th ed. NJ: Merck and Co., Whitehouse Station; 2010.

Constable PD, Walker PG, Morin DE, Foreman JH. Clinical and laboratory assessment of hydration status of neonatal calves with diarrhea. J Am Vet Med Assoc. 1998;212(7):991-996. PMID: 9540870

Renaud DL, Duffield TF, LeBlanc SJ, Ferguson S, Haley DB, Kelton DF. Risk factors associated with mortal- ity at a milk-fed veal calf facility: A prospective cohort study. J Dairy Sci. 2018;101(3):26592668. https://doi. org/10.3168/jds.2017-13581

EMA/EFSA. EMA and EFSA Joint Scientific Opinion on measures to reduce the need to use antimicrobial

agents in animal husbandry in the European Union, and the resulting impacts on food safety (RONAFA). 2016. Available from: https://www.efsa.europa.eu/en/efsa- journal/pub/4666

De Passillé AM, Haley D, Rodas-González A, Borderas

F. Code of Practice for the Care and Handling of veal Cattle: Review of Scientific Research on Priority Is- sues. National Farm Animal Care Council (NFACC), Canada. 2016. Available from: https://www.nfacc.ca/ codes-of-practice/veal-cattle

Veal Cattle Code of Practice Scientific Committee (VC- CPSC). Code of Practice for the Care and Handling of Veal Cattle: Review of Scientific Research on Prior- ity Issues. Lacombe, AB: National Farm Animal Care Council. 2016. Available from: http://www.nfacc.ca/ resources/codes-of-practice/veal-cattle/veal_cattle_ SCreport_2016.pdf

Roland L, Drillich M, Iwersen M. Hematology as a diagnos- tic tool in bovine medicine. J Vet Diagn Invest. 2014;26(5): 592-598. https://doi.org/10.1177/1040638714546490

Council Directive 97/2/EC of 20 January 1997 amend- ing Directive 91/629/EEC laying down minimum stan- dards for the protection of calves. 1997. Available from: http://data.europa.eu/eli/dir/1997/2/oj

Berge ACB, Atwill AR, Sischo WM. Assessing antibiotic resistance in fecal Escherichia coli in young calves using cluster analysis techniques. Prev Vet Med. 2003;61(2):91-

https://doi.org/10.1016/S0167-5877(03)00191-0

Brscic M, Leruste H, Heutinck LF, Bokkers EA, Wolthuis-Fillerup M, Stockhofe N, et al. Prevalence of respiratory disorders in veal calves and potential risk factors. J Dairy Sci. 2012;95(5):2753-2764. https://doi. org/10.3168/jds.2011-4699

Pardon B, De Bleecker K, Hostens M, Callens J, Dewulf J, Deprez P. Longitudinal study on morbidity and mor- tality in white veal calves in Belgium. BMC Vet Res. 2012;8(1):26. https://doi.org/10.1186/1746-6148-8-26

Taylor JD, Fulton RW, Lehenbauer TW, Step DL, Con- fer AW. The epidemiology of bovine respiratory disease: What is the evidence for predisposing factors. Can Vet J. 2010;51(10):1095-1102. PMCID: PMC2942046

Pempek J, Trearchis, D, Masterson M, Habing G, Proud- foot K. Veal calf health on the day of arrival at growers

in Ohio. J Anim Sci. 2017;95(9):3863-3872. https://doi. org/10.2527/jas2017.1642

Wilson LL, Smith JL, Smith DL, Swanson DL, Drake TR, Wolfgang DR, et al. Characteristics of veal calves upon arrival, at 28 and 84 days, and at end of the produc- tion cycle. J. Dairy Sci. 2000;83(4):843-854. https:// doi.org/10.3168/jds

Pardon B, Alliët J, Boone R, Roelandt S, Valgaeren B, Deprez P. Prediction of respiratory disease and diarrhea in veal calves based on immunoglobulin levels and the serostatus for respiratory pathogens measured at ar- rival. Prev Vet Med. 2015;120(2):169-176. https://doi. org/10.1016/j.prevetmed.2015.04.009

Bähler C, Steiner A, Luginbühl A, Ewy A, Posthaus H, Strabel D, et al. Risk factors for death and unwanted early slaughter in Swiss veal calves kept at a specific animal welfare standard. Res Vet Sci. 2012;92:162–168. https://doi.org/10.1016/j.rvsc.2010.10.009

Thompson PN, Stone A, Schultheiss WA. Use of treat- ment records and lung lesion scoring to estimate the effect of respiratory disease on growth during early and late finishing periods in South African feedlot cattle. J Anim Sci. 2006;84(2):488-498. https://doi. org/10.2527/2006.842488x

Stanton AL, Kelton DF, Leblanc SJ, Millman ST, Wor- muth J, Dingwell RT, et al. The effect of treatment with long-acting antibiotic at postweaning movement on respiratory disease and on growth in commercial dairy calves. J Dairy Sci. 2010;93(2):574-581. https://doi. org/10.3168/jds.2009-2414

Thrall MA. Veterinary Hematology and Clinical Chem- istry. Baltimore: Lippincott Williams and Wilkins; 2004. pp. 45-46.

Friedrichs KR, Harr KE, Freeman KP, Szladovits B, Walton RM, Barnhart KF, et al. ASVCP reference inter- val guidelines: determination of de novo reference in- tervals in veterinary species and other related topics. Vet Clin Pathol, 2012;41:441-453. https://doi.org/10.1111/ vcp.12006

Meyer DJ, Harvey JW. Veterinary Laboratory Medi- cine: Interpretation and Diagnosis, Third ed., St. Louis: Saunders; 2004. 5 p.

Zanker IA, Hammon HM, Blum JW. Delayed feed- ing of first colostrums: are there prolonged effects on

haematological, metabolic and endocrine parameters and on growth performance in calves? J Anim Physiol Anim Nutr (Berl). 2001;85(3-4):53-66. https://doi. org/10.1046/j.1439-0396.2001.00296.x

Mohri M, Sharifi K, Eidi S. Hematology and serum bio- chemistry of Holstein dairy calves: Age related changes and comparison with blood composition in adults. Res in Vet Sci. 2007;83(1):30-39. https://doi.org/10.1016/j. rvsc.2006.10.017

Knowles TG, Edwards JE, Bazeley KJ, Brown SN, But- terworth A, Warriss PD. Changes in the blood bio- chemical and haematological profile of neonatal calves with age. Vet Rec. 2000;147(21):593-598. https://doi. org/10.1136/vr.147.21.593

Jain NC. Schalm’s Veterinary haematology, 4th ed., Philadelphia: Lea and Febiger; 1986.

Tennant B, Harrold D, Reina-Guerra M, Kendrick JW, Laben RC. Hematology of the neonatal calf: erythro- cyte and leukocyte values of normal calves. Cornell Vet. 1974;64(4):516-532. PMID: 4473317

Mohri M, Sarrafzadeh F, Seifi HA, Farzaneh N. Effects of oral iron supplementation on some haematological parameters and iron biochemistry in neonatal dairy calves. Comp Clin Path. 2004;13:39-42. https://doi. org/10.1007/s00580-004-0523-5

Egli CP, Blum JW. Clinical, haematological, metabolic and endocrine traits during the first three months of life of suckling Simentaler calves held in a cow-calf op- eration. J Vet Med A. 1998;45(2):99-118. https://doi. org/10.1111/j.1439-0442.1998.tb00806.x

Panousis N, Siachos N, Kitkas G, Kalaitzakis E, Krit- sepi-Konstantinou M, Valergakis GE. Hematology reference intervals for neonatal Holstein calves. Res Vet Sci. 2018;118:1-10. https://doi.org/10.1016/j. rvsc.2018.01.002

Lindt F, Blum J. Occurrence of iron deficiency in grow- ing cattle. J Vet Med A. 1994;41(3):237-246. https://doi. org/10.1111/j.1439-0442.1994.tb00090.x

Katunguka-Rwakishaya E, Larkin H, Kelly WR. Blood values of neonatal calves, and blood values and live- weight gains of calves fed on different levels of milk replacer. Br Vet J. 1987;143(2):184-90. https://doi. org/10.1016/0007-1935(87)90010-8

Council Directive 2008/119/EC of 18 December 2008 laying down minimum standards for the protection of calves. 2008. Available from: http://data.europa.eu/eli/ dir/2008/119/oj

Giambelluca S, Flore E, Sadocco A, Gianesella M, Vaz- zana I, Orefice T, et al. Evaluation of venous blood gas levels, blood chemistry and haemocytometric parameters in milk fed veal calves at different periods of livestock cycle. Pol J Vet Sci. 2016;19(4):745-52. https://doi. org/10.1515/pjvs-2016-0094

Wilson LL, Egan CL, Drake TR. Blood, growth, and other characteristics of special-fed, veal calves in private cooperation herds. J Dairy Sci. 1994;77(8):2477-2485. https://doi.org/10.3168/jds.S0022-0302(94)77189-7

Stull CL, McDonough SP. Multidisciplinary approach to evaluating welfare of veal calves in commercial fa- cilities. J Anim Sci. 1994;72(9):2518-2524. https://doi. org/10.2527/1994.7292518x

United States Department of Agriculture (USDA). 2007. Dairy 2007, Part I: Reference of dairy cattle health and management practices in the United States, 2007. No. N480.1007. USDA – Animal and Plant Health Inspec- tion Service – Veterinary Services, Center for Epidemiol- ogy and Animal Health, Fort Collins, CO. Available from: https://www.aphis.usda.gov/animal_health/nahms/ dairy/downloads/dairy07/Dairy07_dr_PartI_1.pdf

Gygax M, Hirni H, Zwahlen R, Lazary S, Blum JW. Immune functions of veal calves fed low amounts of iron. J Vet Med A. 1993;40(5):345-358. https://doi. org/10.1111/j.1439-0442.1993.tb00638.x

Postema HJ, Mol J. Risk of disease in veal calves: relationships between colostrum-management, serum immunoglobulin levels and risk of disease. J Vet Med A. 1984;31(10):751- 762. https://doi.org/10.1111/j.1439-0442.1984.tb01334.x

Donovan GA, Dohoo IR, Montgomery DM, Bennett FL. Calf and disease factors affecting growth in female Holstein calves in Florida. USA. Prev Vet Med. 1998;33(1–4):1-10. https://doi.org/10.1016/S0167-5877(97)00059-7

Schneider MJ, Tait RG Jr, Busby WD, Reecy JM. An evaluation of bovine respiratory disease complex in feedlot cattle: Impact on performance and carcass traits using treatment records and lung lesion scores. J Anim Sci. 2009;87(5):1821-1827. https://doi.org/10.2527/ jas.2008-1283

Dirksen G, Grunder HD, Stober M. Medicina interna e chirurgia del bovino. 4th ed., Milan: Le point veterinaire Italie srl; 2004.

Hugi D, Blum JW. Changes of blood metabolites and hormones in breeding calves associated with wean- ing. J Vet Med A. 1997;44(2):99-108. https://doi. org/10.1111/j.1439-0442.1997.tb01091.x

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Derechos de autor 2025 Monica Maria Baquero Parra , Felipe Antonio García Amórtegui, Dumar A. Jaramillo-Hernández (Autor/a)

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Palabras clave

eritrograma
análisis de laboratorio
medicina interna
trombograma

Cómo citar

Baquero Parra , M. M. ., García Amórtegui, F. A. ., & Jaramillo-Hernández, D. A. . (2025). Hematological Reference Intervals Milk-Fed Calves During the First Four Weeks upon Arrival to the Farm. Revista De Medicina Veterinaria, 50. https://doi.org/10.19052/mv.vol1.iss50.5129