Effects of Moderate Hypothermia in Canine Blood Glucose Concentrations

Abstract

With the purpose of evaluating variations in the blood glucose of dogs subjected to moderate hypothermia, eight adult dogs were used, anesthetized with etomidate and isoflurane and subjected to three temperature ranges: 32-33 °C, 34-35 °C and 38.5 ± 1 °C normothermia for 150 minutes. The serum glucose of these animals was assessed at baseline and every 30 min during the experimental period. Blood glucose was higher during 6 90 and 120 min, compared with basal concentrations; it was similar in the temperature ranges studied and was always within the range for the species. The application of moderate hypothermia does not alter glucose concentrations, which constitutes an important aspect in neuroprotection.
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Keywords

induced hypothermia
hyperglycemia
anesthesia
cranial trauma