Resumen
Este estudio evaluó la ocurrencia de azotemia y la relación entre azotemia, raza, sexo y edad en perros que llevados para tratamiento veterinario a un hospital veterinario de tercer nivel en Nigeria del este. Un total de 304 perros de diversas razas y edades, machos y hembras, fueron evaluados en este estudio. La disfunción renal se determinó evaluando los niveles de creatinina sérica, usando los criterios de la Sociedad Internacional de Interés Renal para el diagnóstico de disfunción renal, se usó un valor de creatinina sérica de corte ≥ 1.4 mg/dl para clasificar a los perros como positivos para azotemia o no. Los resultados mostraron que 34 (11.2%) perros de la muestra tenían azotemia. Se encontraron variaciones significativas (p < 0.05) en la ocurrencia de azotemia entre razas, los perros caucásicos tuvieron la mayor ocurrencia (5.9%), seguidos del mastín (2.6%), mongrel (2.0%) y alsaciano (0.7%). La ocurrencia de azotemia fue significativamente mayor (p<0.05) en hembras que en machos. Se encontró una variación significativa (p<0.05) en la ocurrencia de azotemia entre los grupos de edad, los perros jóvenes tienen una mayor ocurrencia que los cachorros y los adultos.Referencias
Chew DJ, DiBartola SP, Schenck PA. Familial renal disease in dogs and cats. 6th ed. Oxford: Elsevier Saunder. 2005.1819-1824.
Humphris D, Reyers F, Lobetti RG, Descally MP. Are urea and creatinine values reliable indicators of azotaemia in caninie babesiosis. J S Afr Vet Assoc. 2004;75(3):121-124. https://doi.org/10.4102/jsava.v75i3.466
Ihedioha JI, Chineme CN. Fundamentals of Systemic Veterinary Pathology Vol. 1 Great AP Express Publishers Limiter, Nigeria; 2004. Part 4, Hematopoietic system; p.107-160.
Newman SJ, Confer AW, Pancier RJ. Urinary System. In: MacGavin, M. D., & Zachary, J. F. U, editors. Pathologic Basis of Veterinary Diseases. Mossly: Elsevier Inc; 2007. P. 613-650.
Polushin YuS, Sokolov DV. Kidney dysfunction in critically ill patients. Messenger Anesthesiol Resusc. 2018;15(5):54-64. https://doi.org/10.21292/2078-5658-2018-15-5-54-64
Mazzaferro EM, Ford RB. Kirk and Bistner’s handbook of veterinary procedures and emergency treatment. 9th Ed. Elsevier; 2012. https://doi.org/10.1016/C2009-0-59980-1
Braun JP, Lefebvre HP, Watson AD. Creatinine in dogs. A review. Vet Clin Pathol. 2003;193(4):457-464. https://doi.org/10.1111/j.1939-165X.2003.tb00332.x
Fischer JR, Lane IF, Stokes J. Acute post renal Azotemia: Etiology, clinicopathology and Pathophysiology. Compend Contin Educ Vet. 2009;31(11):520-524.
Zhang Q. Rothenbacher D. Prevalence of chronic kidney disease in population – based studies: Systematic review. BMC Public health. 2008;8(1):117. https://doi.org/10.1186/1471-2458-8-117
Chukwuonye I I, Ogah OS, Anyabolu EN, Ohagwu KA, Nwabuko OC, Onwuchekwa U, et al. Prevalence of chronic kidney disease in Nigeria: Systematic review of population- based studies. Int J Nephrolog Renovasc Dis. 2018;(11):65-172. https://doi.org/10.2147/IJNRD.S162230
Elhafeez SA, Boligano D, D’Arrigo G, Dounousi E, Tripepi G, Zoccali, C. Prevalence and burden of chronic kidney disease among the general population and high- risk groups in Africa. A systematic Review. BMJ Open. 2017;8(1):e015068. https://doi.org/10.1136/bmjopen-2016-015069
Ross SJ, Osborne CA, Kirk CA, Lowry SR, Koehler LA, Polzin, DJ. Clinical Evaluation of Dietary Modification for Treatment of Spontaneous Chronic Kidney Disease in Cats; J Am Vet Med Assoc. 2006;229(6):949-957. https://doi.org/10.2460/javma.229.6.949
Bartlett PC, Van Buren JW, Bartlett AD, Zhou C. Case–control study of risk factor associated with feline and canine chronic kidney disease. Vet Med Internation. 2010:957570. https://doi.org/10.4061/2010/957570
Pelander L, Ljunguall L, Egenvall A, Syme H, Elliot J, Häggström J. Incidence of and mortality from kidney disease in over 600000 insured Swedish dogs. Vet Rec. 2015176(25)656. https://doi.org/10.1136/vr.103059
Kandala S, Karlapudi K. Prevalence of renal disorders in dogs—A clinical study. Int J Agric Sci Vet Med. 2014;2(3)146-148. https://citeseerx.ist.psu.edu/document?repid=rep1&type=pdf&doi=1fd25807a255e16a64276fa0abe253f8078e8af3
O’Neil DG, Elliot J, Church DB, McGreeny PD, Thomas PC, Brodbett DC. Chronic Kidney disease in dogs in UK veterinary practice. Prevalence, risk factors and survival. J Vet Internal Med. 2013;27(4):814-821. https://doi.org/10.1111/jvim.12090
Nnamdi HO, Udegbunam RI, Emejuo NT, Udegbunam SO. Changes in selected haematology and serum biochemistery parameters associated with surgically managed tooth avulusion in a dog: Case Report. J Vet Applied Sci. 2019;9(1):32-35. http://jvasonline.com/JVAS%202018%20063%20F.pdf
Blass KA, Thiebert RJ, Lam LK. A study of the mechanism of Jaffe reaction. J Clin Chem. 1974;12(7):336-343. https://doi.org/10.1515/cclm.1974.12.7.336
Lamb EJ, Price CP. Creatinine, urea and uric acid. In: Burtis, C.A., Ashwood ER, Bruns, DE, editors. Tietz fundamentals of clinical chemistry. 6th ed. Miaaouri: Elsevier, 2008. p. 363-372.
IRIS. IRIS Staging of CKD [internet]. International Renal Interest Society; 2015. Available from: http://www.iris-kidney.com/guidelines/staging.html
Brown SA. Management of chronic kidney disease. In Elliot J., Grauer C.F (eds) BSAVA manual of canine and feline nephrology and urology. 2nd ed. Glorcester: British Small Animal Veterinary Association; 2007. 223 p.
Pelander L. Chronic kidney disease in dogs: Pathophysiological mechanism and diagnostic aspects [dissertation]. [Uppsala]: Swedish University of Agricultural Science; 2018. Available from: https://res.slu.se/id/publ/100498
Mshelbwala FM, Ajayi OL, Adebiyi AA, Olaniyi MO, Omotainse SO, Kadiri AK. Retrospective studies on the prevalence, morphological, pathological and aetiology of renal failure of dogs in Lagos and Abeokuta, Nigeria. Nigerian Vet J. 2016;37(4):208-2016. Available from: https://www.ajol.info/index.php/nvj/article/view/163811
Ahmed, SA. Incidence of renal disorders in canines, evaluating prognostic markers in gentamicin induced nephrotoxic dogs [thesis]. [Izatnagar]: Indian Veterinary Research Institute; 2011.
Ihedioha JI, Enahoro G. Prevalence of diabetes mellitus and reference values for fasting blood glucose levels of locally available dogs in Warri, Nigeria. Comp Clin Pathol. 2019;28:1107-1112. https://doi.org/10.1007/s00580-019-02938-7
Lund EM, Armstrong PJ, Kirk CA, Kolar LM, Klausnar JS. Health status and population characteristics of dogs and cats examined at a private veterinary practice in the United States. J Am Vet Med Assoc. 1999;24(9):1336-1341.
Sosnar M, Kohout PJ, Ruicka M, Vibasova L, (2003). Retrospective study of renal failure in dogs and cats admitted to university of Veterinary Pharmaceutical Science, Brno during 1999-2001. Acta Vet Brno. 2003;72(4):593-598. https://doi.org/10.2754/avb200372040593
Nabi SU, Dey S, Shah OS, Hussain T, Amin U, Vala J, et al. Incidence of renal disorders in canines and its relationship with age breed and sex. Pharma Innov J. 2018;7(1): 87-89. https://www.thepharmajournal.com/archives/2018/vol7issue1/PartB/7-1-8-406.pdf
Polzin DJ. Chronic kidney disease In: Ettinger SJ, Feldman EC, editors. Textbook of veterinary internal medicine: Diseases of dogs and cats. St. Louise MO: Elsevier; 1990
Grauer GF, Lane IF. Acute renal failure: Ischemic and chemical nephrosis. Osborne CA, Finco DR, editors. Canine nephrology and urology. Baltimore: Lea and Febiger 1995. p. 441-459.
Hall JL, Holmes A, Baines ST. Prevalence and antimicrobial resistance of canine urinary tract pathogens. Vet Rec. 2013;173(22);549. https://doi.org/10.1136/vr.101482
Geerlings SE. Clinical presentation and epidemiology of urinary tract infection. In: Mulvey Ma, Klumpp, DJ, Stapleton, AE, editors. Urinary tract infections: Molecular pathogenesis and clinical management, 2nd ed. Washington: American Society for Microbiology; 2016. https://doi.org/10.1128/9781555817404.ch2
Puchot ML, Cook AK, Pohlit C. Subclinical bacteria in cats: Prevalence findings on contemporaneous urinalysis and clinical risk factors. J Feline Med Surgery. 2017;11:1238-1244. https://doi.org/10.1177/1098612X16688806
Kivisto AK, Vasenius H, Sandholm M. Canine bacteruria. J Small Animal Practice. 1977;18(11):707-712. https://doi.org/10.1111/j.1748-5827.1977.tb05843.x
Mayer-Roenne B, Goldstern RE, Erb HN (2007). Urinary tract infection in cats with hyperthyroidism, diabetes mellitus and chronic kidney disease. J Feline Med Surgery. 2007;9(2):124-132. https://doi.org/10.1016/j.jfms.2006.09.004
Thompson MF, Litster AL, Platell JL. Trott DJ. Canine bacterial urinary tract infection: New developments in old pathogens. Vet J. 2011;190(1):22-27. https://doi.org/10.1016/j.tvjl.2010.11.013
Bjorling DE. The urethra In: Slatter D, editor. Textbook of small animal surgery. Philadelphia: Saunders; 2003. p. 1638-1651.
Palabras clave
edad
sexo
razas