Efficacy of Doramectin Via Intramuscular Injection in Gastrointestinal Nematodes in Horses

Abstract

This research aimed to test the effectiveness of doramectin by intramuscular administration against nematodes of horses, as it is evacuated, observed in the reduction in egg counts per gram of feces (epg). To this end, six donkeys and ten mestizo horses of different sexes and ages were used, all naturally infected with gastrointestinal nematodes. Animals were randomly divided into two groups: 1 (control), three donkeys and four horses that didn’t receive anthelmintic treatment and 2 (treated), three donkeys and six horses treated with doramectin at a dose of 0.2 mg/kg by intramuscular administration, single dose, applied on the neck. At days 5, 12, 16, 24, 34, 41, 47, 56, 60 and 140 post-treatment all animals were subjected to stool tests, allowing to define epg values by McMaster technique. The results determined that doramectin by intramuscular administration was highly effective in controlling nematodes in field conditions and in animals subjected to continual reinfestation.